Early Lactate Clearance is Associated with Improved Outcome in Severe Sepsis and Septic Shock
نویسندگان
چکیده
منابع مشابه
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
OBJECTIVE Serial lactate concentrations can be used to examine disease severity in the intensive care unit. This study examines the clinical utility of the lactate clearance before intensive care unit admission (during the most proximal period of disease presentation) as an indicator of outcome in severe sepsis and septic shock. We hypothesize that a high lactate clearance in 6 hrs is associate...
متن کاملIs lactate clearance impaired in septic shock?
In a recent article in Critical Care, Tapia and colleagues evaluated the relationship between exogenous lactate clearance and liver perfusion in a short-term model of endotoxemic shock [1]. The authors concluded that the very low portal-hepatic vein lactate gradient was indicative of the inability of the liver to metabolize the increased lactate load. Although we believe that the authors addres...
متن کاملSevere sepsis and septic shock
Morbidity and mortality from sepsis remains unacceptably high. Large variability in clinical practice, plus the increasing awareness that certain processes of care associated with improved critical care outcomes, has led to the development of clinical practice guidelines in a variety of areas related to infection and sepsis. The Surviving Sepsis Guidelines for Management of Severe Sepsis and Se...
متن کاملSevere sepsis and septic shock.
From the CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illness) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh (D.C.A.); and the Center for Experimental and Molecular Medicine, Division of Infectious Diseases, and Center for Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Amsterd...
متن کاملUnderweight is associated with mortality in patients with severe sepsis and septic shock
Methods A retrospective analysis of prospectively collected database of patients with severe sepsis and septic shock was performed. We classified the patients into four groups according to the basic criteria of the World Health Organization (WHO) guidelines as follows, underweight, < 18.5; normal, 18.5-24.99; overweight, 25-29.99; obesity, ≥ 30 kg/m, respectively. The multivariate logistic regr...
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ژورنال
عنوان ژورنال: Journal of the Intensive Care Society
سال: 2005
ISSN: 1751-1437
DOI: 10.1177/175114370500600222